ARTēVA® pinch valves.
316L stainless pinch head machined in Carson City. Manual, pneumatic, and eMaxion™ electric on the same proven mechanism, across ⅛" to 1" tubing ID. Engineered Aquasyn × Alphinity.
Three actuation options on one pinch head. Reusable 316L stainless mechanism with disposable single-use tubing when the wetted path needs to stay compliant.
Three actuation modes · one pinch head.
Manual handwheel, pneumatic spring-return or double-acting, eMaxion™ electric. All three mount on the same 316L stainless pinch architecture, so the choice is about process control fit · not about retooling the line.
Handwheel · no infrastructure.
Operator-driven pinch close. The Manual variant requires no compressed-air, no electrical, no positioner. Clamp on, connect tubing, operate. Right for process development, screening, small-scale sterile operations, and benchtop work.
Spring-return or double-acting.
Production-grade pneumatic actuation. Spring-return for fail-safe service, double-acting for tight control across both directions. Integrates with existing Aquasyn pneumatic infrastructure and the same positioner architecture used on the diaphragm line.
Closed-loop electric modulating.
Bipolar stepper with encoder, thousands of micro-steps, M12 connectors for SCADA, PLC, and Pharma 4.0 integration. No compressed-air utility, no air-quality validation. The same eMaxion that drives the Aquasyn diaphragm line, mounted on the ARTēVA® pinch head.
The hybrid mechanism.
One reusable 316L stainless steel encapsulated pinch head. One single-use disposable tubing flow path. Three actuation options on the same body. The architecture that lets a process keep stainless actuation discipline while running a disposable wetted path.
Every ARTēVA® variant shares the same fundamental architecture. The pinch head is encapsulated stainless · hygienic, corrosion-resistant, autoclavable, and built for repeated use, cleaning, and long-term performance in demanding bioprocess environments. The wetted flow path is single-use tubing, replaced between batches. Sterility is maintained by tubing replacement, not by cleaning validation of the pinch head.
Reusable pinch head
- 316L stainless steel construction
- Encapsulated, hygienic geometry
- Corrosion-resistant for bioprocess
- Autoclavable for repeated use
- Central pinch design
- Minimized wear on tubing and body
Single-use flow path
- Disposable wetted tubing
- Replaced between batches
- No cleaning validation required
- Sterility by replacement
- Vendor-validated tubing options
- Single-use compliance maintained
Tubing compatibility.
ARTēVA® supports unbraided tubing in inside diameters from ⅛" to 1", across silicone and TPE single-use tubing formats. Tubing is validated by the tubing vendor; no separate ARTēVA® validation is required for the wetted flow path.
The central pinch geometry minimizes wear on the tubing wall, supporting closure reliability over 10,000+ cycles. Compatible with the major single-use bioprocess tubing manufacturers; the tubing is the disposable, the pinch head is the asset. Tubing change-over is the same operation as any pinch-valve recommission · no instrument calibration, no pinch-head removal, no actuator recalibration.
Unbraided silicone or TPE is the standard specification and needs no qualification. Braided and reinforced walls are stiffer, which is what the pinch head has to overcome, so send us a sample of the tubing you intend to use and we will test it before anything ships. Double-braid is the one that gives us trouble. If the line pressure is high enough that you need heavy reinforcement, a diaphragm valve is usually the better answer.
Which tubing for which process.
Every tubing material has a different chemistry, temperature envelope, and cycle profile. The pinch mechanism is the same across both · this guide helps pick the wetted flow path.
Where ARTēVA® does the work.
Used across upstream and downstream bioprocessing · anywhere a reliable, hygienic pinch valve is needed with single-use tubing compatibility. Twelve application categories, one valve architecture.
Media & Buffer Transfer
Sterile transfer lines for media, feed solutions, and buffer addition into upstream stages.
Cell Culture Feed Lines
Controlled dosing into bioreactors and cell culture vessels without contaminating the main stream.
Perfusion Circuits
Continuous-feed perfusion lines where the wetted path must remain disposable across long campaigns.
Bioreactor Inlet / Outlet
Stainless-actuation discipline on the bioreactor's wetted-path interface, with single-use tubing.
Filtration Systems
Filtration manifolds where stainless rigidity is needed at the pinch but the flow path stays single-use.
Chromatography Systems
Switching, diversion, and column-inlet control where modulating precision and tubing compatibility both matter.
Harvest & Collection
Hygienic switching of harvested product paths between collection vessels.
Viral Inactivation Hold
Hold-step isolation valves where contamination of the bulk product line cannot be tolerated.
Final Fill Workflows
Aseptic transfer into final-fill stations with closed-tubing flow paths.
Sampling Points
Quick, reliable switching for sample draw without contaminating the main product stream.
Bypass & Diversion
Bypass operations and diversion paths where rapid, repeatable switching is required.
Process Development
Screening and small-scale sterile operations. Manual variant requires no infrastructure · clamp on, connect tubing, operate.
Specifications and configuration.
The full configurability table across all three actuation modes. Specify by tubing ID, actuation, pressure class, and integration option.
Tell us where you're running disposables.
Manual, pneumatic, or eMaxion™ electric. ⅛"–1" silicone or TPE tubing, braided on verification. Configure once · the same pinch head carries every actuation choice.